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A team made up by researchers of
the ICO and the University Hospital in Bellvitge has studied the
TP53 gene as a factor in the prognostic of the metastases in the
liver of a primary colon cancer. In this sense, and after having
been operated to extirpate the tumour that has reproduced in the
liver, the patients with the mutated TP53 gene have a worse prognostic.
The results are based in the widest consecutive series of patients
(91 patients) and most homogeneous (they have been operated and treated
by the same teams of the Institut Català d’Oncologia
and the University Hospital in Bellvitge) of all the studies that
have taken place so far. Carcinogenesis: "Mutations in TP53
are a prognostic factor in colorectal hepatic metastases undergoing
surgical resection", published on 27th of January in the on-line
edition, and on paper, in the February issue. (Carcinogenesis. Doi:
10.1093/carcin/bgm012).
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